UBB monoclonal antibody, clone 3C12
产品名称: UBB monoclonal antibody, clone 3C12
英文名称: UBB monoclonal antibody, clone 3C12
产品编号: MAB10342
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant UBB.
- Immunogen:
- Recombinant protein corresponding to human UBB.
- Host:
- Mouse
- Theoretical MW (kDa):
- 26
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.5% protein stabilizer, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using UBB monoclonal antobody, clone 3C12 (Cat # MAB10342) against NIH/3T3 (1) and HeLa (2) cell lysate.
- Entrez GeneID:
- 7314
- Gene Name:
- UBB
- Gene Alias:
- FLJ25987,MGC8385
- Gene Description:
- ubiquitin B
- Omim ID:
- 191339
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq
- Other Designations:
- OTTHUMP00000064960,OTTHUMP00000064961,polyubiquitin B
- Gene Pathway